Week 2 · 2026 Season
Date
Thu, Sep 17, 2026
Week 2
Kickoff
8:15 PM ET
Location
Highmark Stadium
Orchard Park, New York
Line
—
Week 2 · 2026 Season
Date
Thu, Sep 17, 2026
Week 2
Kickoff
8:15 PM ET
Location
Highmark Stadium
Orchard Park, New York
Line
—
Detroit Lions
1-2 SU
Buffalo Bills
2-1 SUFull matchup analysis
11-on-11 depth-chart breakdown, key positional edges, betting splits.
| 2018-12-16· Wk 15 |
| BUF 14–13 |
CoverUnder |
| 2014-10-05· Wk 5 | BUF 17–14 | MissUnder |
| 2010-11-14· Wk 10 | BUF 14–12 | MissUnder |