San Francisco 49ers at Indianapolis Colts | Week 16, 2025 | League Station

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HomeScheduleSFO at IND

Week 16 · 2025 Season· FINAL

San Francisco 49ers

10-4 · NFC West

Final

Indianapolis Colts

8-6 · AFC South

Date

Mon, Dec 22, 2025

Week 16

Kickoff

8:15 PM ET

Location

Lucas Oil Stadium

Indianapolis, Indiana

Result

SFO 48, IND 27

Overview
Box Score
Team Stats
Play-by-Play
Madden Edge
Coaching

Roster Strength · Madden

San Francisco 49ers

Starter Avg

71.4

top 22 by OVR

Elite

0

players rated 90+

Top Rated

82De'Vondre CampbellLB
75Chris ConleyWR
74Taybor PepperLS
74Tre BrownDB
73Jon FelicianoOL

52 rated players on roster

Indianapolis Colts

Starter Avg

66.8

top 22 by OVR

Elite

0

players rated 90+

Top Rated

73Tre HerndonDB
73David LongDB
72Mark GlowinskiOL
70Duke ShelleyDB
69Juwann WinfreeWR

35 rated players on roster

Full matchup breakdown

11-on-11 depth-chart comparison, key positional edges, and the field visualizer.