Week 16 · 2025 Season· FINAL
Date
Mon, Dec 22, 2025
Week 16
Kickoff
8:15 PM ET
Location
Lucas Oil Stadium
Indianapolis, Indiana
Result
SFO 48, IND 27
Coaching Matchup
San Francisco 49ers- Kyle ShanahanHead Coach
- Klay KubiakOffensive Coordinator
- Robert SalehDefensive Coordinator
Indianapolis Colts- Shane SteichenHead Coach
- Jim Bob CooterOffensive Coordinator
- Lou AnarumoDefensive Coordinator