Week 3 · 2025 Season· FINAL
Date
Sunday, September 21, 2025
Kickoff
4:25 PM
Location
Levi's Stadium · Santa Clara, California
Result
ARI 15 — SFO 16
Betting Outcome
Spread
ARI +1.5 cashed
Total
Under 44 (31)
Heading In · Last 3 Games
Arizona Cardinals
3-0 · 31.3 PPG · 19.7 OPG- W27-22vs CAR
- W20-13@ NOR
- W47-24vs SFO
San Francisco 49ers
2-1 · 22.3 PPG · 27 OPG- W26-21@ NOR
- W17-13@ SEA
- L24-47@ ARI
Top Performers
Arizona Cardinals
- PassingKyler Murray22/35, 159 yds, 1 TD
- RushingTrey Benson10 att, 42 yds
- ReceivingMarvin Harrison Jr.3 rec, 44 yds
San Francisco 49ers
- PassingMac Jones27/41, 284 yds, 1 TD, 1 INT
- RushingChristian McCaffrey17 att, 52 yds
- ReceivingRicky Pearsall8 rec, 117 yds