Week 2 · 2001 Season· FINAL
Date
Sunday, September 23, 2001
Kickoff
1:00 PM
Location
Lucas Oil Stadium · Indianapolis, Indiana
Result
BUF 26 — IND 42
Betting Outcome
Spread
IND covered −10
Total
Over 44.5 (68)
Heading In · Last 3 Games

Buffalo Bills
1-2 · 19.3 PPG · 20 OPG- L6-24vs NOR
- W42-23@ SEA
- L10-13vs NWE

Indianapolis Colts
3-0 · 32 PPG · 15.7 OPG- W45-24@ NYJ
- W31-10vs MIN
- W20-13@ MIA
Top Performers

Buffalo Bills
- PassingRob Johnson24/37, 257 yds, 1 TD, 1 INT
- RushingRob Johnson5 att, 63 yds
- ReceivingLarry Centers7 rec, 56 yds

Indianapolis Colts
- PassingPeyton Manning23/29, 421 yds, 4 TD, 2 INT
- RushingEdgerrin James23 att, 111 yds, 1 TD
- ReceivingJerome Pathon9 rec, 168 yds, 1 TD