San Francisco 49ers at Kansas City Chiefs | Week 16, 2026

San Francisco 49ers at Kansas City Chiefs | Week 16, 2026 | League Station

Heading In · Last 3 Games

San Francisco 49ers

2-1 SU

2-1 ATS2-1 O/U31 PPG26 OPG

Kansas City Chiefs

0-3 SU

1-2 ATS0-3 O/U11.3 PPG20 OPG

Last 5 meetings · SFO 1–4 KAN SU

0-4-1 ATS (SFO)3-2 O/U

Date	Week	Result	ATS · O/U
2024-10-20· Wk 7	2024 Wk 7	KAN 28–18	MissUnder
2022-10-23· Wk 7	2022 Wk 7	KAN 44–23	MissOver
2018-09-23

Full matchup analysis

11-on-11 depth-chart breakdown, key positional edges, betting splits.