San Francisco 49ers at Los Angeles Rams | Week 1, 2026

San Francisco 49ers at Los Angeles Rams | Week 1, 2026 | League Station

Heading In · Last 3 Games

San Francisco 49ers

2-1 SU

2-1 ATS2-1 O/U31 PPG26 OPG

Los Angeles Rams

1-2 SU

2-1 ATS3-0 O/U32.7 PPG28.3 OPG

Last 5 meetings · SFO 1–4 LAR SU

1-4 ATS (SFO)4-1 O/U

Date	Week	Result	ATS · O/U
2025-11-09· Wk 10	2025 Wk 10	LAR 42–26	MissOver
2025-10-02· Wk 5	2025 Wk 5	SFO 26–23	CoverOver

Full matchup analysis

11-on-11 depth-chart breakdown, key positional edges, betting splits.